Poly-L-ornithine
Options: HCL or HBr
CAS No: 27378-49-0
Molecular weight: 15-150K Da
Purity: 99.9%
Appearance: white solid
Minimal order quantity: 10 gram
Poly-L-ornithine is a biocompatible, positively charged polymer made from the amino acid ornithine, known for its excellent properties in cell culture and tissue engineering. This versatile material enhances cell adhesion, making it a valuable tool for a variety of applications in biomedical research, drug delivery systems, and medical device coatings.
In cell culture, Poly-L-ornithine is often used to coate surfaces, providing a stable and adhesive environment for primary cells, stem cells, and neuronal cells. Its ability to support cell attachment and growth is essential for experiments that require consistent and high-quality cell behavior. Poly-L-ornithine is particularly effective for neuron culture, facilitating neural differentiation and neuronal network formation.
This polymer also plays an important role in tissue engineering by promoting cell adhesion to scaffold materials, supporting regenerative medicine applications, and contributing to the development of engineered tissues. Moreover, its biodegradable nature makes it a promising candidate for controlled drug delivery and other bioengineering applications.
With its high purity, biocompatibility, and ability to enhance cell adhesion and growth, Poly-L-ornithine is a key material in advancing biomedical technologies and improving the success of cell-based therapies and tissue regeneration.
FAQ
Most frequent questions and answers
Poly-L-ornithine is used as a coating for cell culture surfaces, enhancing cell adhesion and promoting the growth of various cell types, including neuronal cells and stem cells. It provides a stable surface for cells to attach to, improving the consistency and quality of cell-based experiments. This is especially useful for studies in neuroscience and regenerative medicine.
Yes, Poly-L-ornithine is widely used to culture neuronal cells. It promotes neuronal attachment and growth, making it ideal for neuroscience research, including studies on neural differentiation, neural networks, and neurodegenerative diseases. Poly-L-ornithine helps create a conducive environment for neuronal cultures to thrive.
Yes, Poly-L-ornithine is highly effective for promoting the attachment and growth of stem cells. It is often used in stem cell culture systems, where it enhances the adhesion and proliferation of pluripotent stem cells and adult stem cells. This makes it a valuable tool in regenerative medicine and cell-based therapies.
Yes, Poly-L-ornithine plays an important role in tissue engineering by promoting cell adhesion to scaffolds. It helps ensure that cells grow and integrate properly within engineered tissues. Its ability to improve cell-material interactions makes it a useful material in the development of regenerative therapies and bioengineered tissues.
Yes, Poly-L-ornithine is biodegradable, which makes it suitable for applications like drug delivery and tissue engineering, where controlled degradation over time is essential. This biodegradability ensures that it will not accumulate in the body or interfere with natural biological processes.
The shelf life of Poly-L-ornithine is typically around 2-3 years if stored under recommended conditions. It should be kept in a cool, dry place away from direct sunlight and moisture to maintain its effectiveness and purity.
Poly-L-ornithine should be stored in a cool, dry environment and sealed in an airtight container to protect it from moisture and contaminants. It is recommended to store it at 2°C to 8°C to preserve its quality over time.
Yes, Poly-L-ornithine can be used in drug delivery systems due to its ability to enhance cell adhesion and facilitate controlled release. Its biodegradable nature also makes it suitable for use in biodegradable drug carriers and tissue-targeting drug delivery applications.