High-Purity p-Dioxanone (PDO Monomer) for Advanced Biomedical Applications
Why Choose Our p-Dioxanone?
Exceptional Purity
≥99.5% (GC), suitable for medical-grade polymer synthesis.
Bulk Supply Capability
Scalable production from R&D quantities to commercial metric tons.
Strict Quality Control
Low moisture and acid content to prevent premature polymerization.
Competitive Pricing
Direct manufacturing supply ensures cost-effectiveness.
nhance Flexibility and Control Degradation in Your Polymer Matrix
p-Dioxanone (1,4-dioxan-2-one) is a colorless, crystalline cyclic ester-ether monomer. Unlike standard polylactides, polymers made from p-Dioxanone offer unique flexibility, shape memory, and an intermediate degradation profile (typically 6 months).
Our high-purity monomer is meticulously refined to remove impurities that affect polymerization rates. Whether you are producing monofilament sutures that require high tensile strength and flexibility, or developing complex copolymers (e.g., with Glycolide or Lactide) for drug delivery, our p-Dioxanone serves as the reliable building block you need.
Specifications for p-Dioxanone
| Property | Specification |
|---|---|
| CAS Number | 3041-16-5 |
| Appearance | White solid |
| Purity | ≥ 99.5% (Medical Grade) |
| Melting Point | 27-30°C |
| Water residue | ＜200ppm |
| Free acid | ≤2mmol/kg |
| Total heavy metal content | ≤10ppm |
FAQ
Most frequent questions and answers
Yes. We offer standard packaging in aluminum foil vacuum bags (1kg, 5kg) and fiber drums (25kg) with double PE liners. Custom packaging solutions are available to ensure stability during transport.
The monomer is soluble in common organic solvents such as Ethyl Acetate, Chloroform, Dichloromethane, Toluene, and Benzene. It generally has low solubility in aliphatic hydrocarbons (like Hexane) and water (though exposure to water triggers hydrolysis).
While we recommend storage at low temperatures, short-term exposure to ambient temperature during shipping is generally acceptable if the packaging is strictly sealed against moisture. For critical medical-grade orders, cold chain logistics can be arranged.
Yes. It is frequently copolymerized with Glycolide (to increase degradation rate), L-Lactide (to increase stiffness), or Trimethylene Carbonate (TMC) (to improve elasticity). These copolymers allow formulators to “dial in” specific degradation times and mechanical properties.
The ether oxygen in the backbone imparts flexibility to the polymer chain, which is why Polydioxanone (PDO) is significantly more flexible and less stiff than Polyglycolic Acid (PGA) or Polylactic Acid (PLA), making it ideal for monofilament sutures that must pass through tissue smoothly.
Yes. We define our medical grade by specific purity parameters: Purity >99.5%, low heavy metal content, and strict limits on residual solvents and water. This grade is specifically designed for the synthesis of bioresorbable medical devices.
Yes. Polydioxanone (synthesized from our monomer) is increasingly used in 3D printing filaments and electrospinning for tissue engineering due to its excellent shape memory and biocompatibility.
Yes, but less aggressively than other polyesters. The polymer degrades into glyoxylic acid and then into glycine and water/CO2. The inflammatory response is generally lower compared to PGA (Polyglycolic acid) because the degradation products are less acidic and accumulate more slowly.
We support R&D projects with quantities as low as 100g or 500g. For pilot and industrial production, we supply in 1kg, 5kg, and 25kg batches.
We use a multi-layer packaging system: usually an inner glass or PP bottle/bag, sealed within an aluminized moisture-barrier bag under vacuum or nitrogen flush, placed inside a sturdy exterior drum or carton.
This monomer is highly hygroscopic and susceptible to hydrolysis. It must be handled in a moisture-free environment, such as a glovebox filled with dry Nitrogen or Argon. Exposure to ambient humidity can rapidly increase the acid value and inhibit polymerization.