Polytrimethylene-carbonate

Poly(Trimethylene Carbonate)

Synonyms: PTMC

Appearance:  Colorless, yellow wish particle

End Group: Acid, Ester and Hydroxyl group for options

Minimal order quantity: 30 gram

Are you looking for a biodegradable, flexible, and hydrophobic polymer for your biomedical or industrial applications? Look no further than our high-quality poly(trimethylene carbonate) (PTMC)!

PTMC is an aliphatic polycarbonate that can be synthesized from the 6-membered cyclic carbonate, trimethylene carbonate (TMC). PTMC has a low glass transition temperature (-15 to -30 °C) and a moderate melting temperature (38 to 41 °C), which give it excellent elasticity and processability.

Our PTMC polymer is customizable, so you can choose the molecular weight and the end group that suit your needs. Whether you need a linear, branched, or star-shaped PTMC, we can synthesize it for you with high precision and efficiency.

We know that poly(trimethylene carbonate)  is not easy to synthesize and can be expensive, but we have a solution for that. We use a novel catalyst and a solvent-free process that reduce the cost and time of production, while maintaining the quality and purity of the polymer. This means you can get more PTMC for less money and faster delivery.

FAQs

There are several ways to improve the mechanical properties of PTMC, such as cross-linking, copolymerization, blending, or adding fillers. These methods can affect the molecular weight, the crystallinity, the morphology, and the interactions of PTMC, and thus change its strength, modulus, elasticity, and toughness.

However, these methods may also have some drawbacks, such as affecting the biodegradability, the biocompatibility, or the processability of PTMC. Therefore, it is important to choose the best method for your specific application and purpose. 

Poly trimethylene carbonate (PTMC) is a biodegradable polymer that has various applications in the field of medicine. It can be used in the production of drug delivery systems, such as nanoparticles, micelles, and implants.

Additionally, PTMC can be used as a scaffold material for tissue engineering and regenerative medicine, as it can support cell growth and tissue regeneration.

Poly trimethylene carbonate (PTMC) is generally considered to have low toxicity. It is biocompatible and has been extensively studied for various medical applications. 

Poly(trimethylene carbonate) degrades by hydrolysis, which is the cleavage of the carbonate bonds by water molecules. The degradation rate and extent depend on several factors, such as the molecular weight, the crystallinity, the morphology, the pH, the temperature, and the presence of enzymes or catalysts. The degradation products are glycolic acid and carbon dioxide, which can be metabolized by the human body.

PTMC is a biodegradable polymer that can be degraded by hydrolysis, which is the cleavage of the carbonate bonds by water molecules1. Therefore, it is important to sterilize PTMC in a way that does not expose it to excessive moisture or heat, which may accelerate its degradation or alter its properties.

One possible method of sterilizing PTMC is by using ethylene oxide (EtO) gas, which is a widely used sterilant for heat-sensitive and moisture-sensitive materials. EtO gas can penetrate the polymer and kill microorganisms without damaging the polymer structure or function. However, EtO gas is also toxic, flammable, and carcinogenic, so it requires special equipment and safety precautions to handle it properly.

Another possible method of sterilizing PTMC is by using gamma irradiation, which is a high-energy electromagnetic radiation that can destroy microorganisms by breaking their DNA. Gamma irradiation can also penetrate the polymer and does not leave any harmful residues. However, gamma irradiation may also cause some changes in the polymer, such as chain scission, crosslinking, oxidation, or discoloration, depending on the dose and the polymer composition. Therefore, it is advisable to test the effect of gamma irradiation on the polymer before using it for sterilization.

A third possible method of sterilizing PTMC is by using plasma, which is a partially ionized gas that contains electrons, ions, and neutral species. Plasma can generate reactive species, such as oxygen radicals, that can inactivate microorganisms on the surface of the polymer. Plasma can also modify the surface properties of the polymer, such as hydrophilicity, wettability, or adhesion, which may be beneficial for some applications. However, plasma may not be able to sterilize the inner parts of the polymer, and may also cause some damage to the polymer surface, such as etching, cracking, or delamination, depending on the plasma parameters and the polymer characteristics.

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