Polyglycolic Acid

Synonyms: Polyglycolide, PGA

CAS No: 26124-68-5

Appearance: yellow particle

Minimal order quantity: 30 gram

Are you looking for a biodegradable, thermoplastic polymer with high strength and stability for your biomedical or industrial applications? Look no further than our high-quality polyglycolide (PGA)!

PGA is a synthetic, aliphatic polyester that can be prepared from glycolic acid by polycondensation or ring-opening polymerization. PGA has a high melting point (225-230°C) and a high degree of crystallinity (45-55%), which give it excellent mechanical properties and resistance to hydrolysis.

Our PGA is customizable, so you can choose the molecular weight that suits your needs. Whether you need a low, medium, or high molecular weight PGA, we can synthesize it for you with high precision and efficiency.

We know that PGA is not easy to synthesize and can be expensive, but we have a solution for that. We use a novel catalyst and a solvent-free process that reduce the cost and time of production, while maintaining the quality and purity of the polymer. This means you can get more PGA for less money and faster delivery.


PGA polymer, or polyglycolic acid polymer, is commonly used in biomedical applications. It is a biodegradable and biocompatible material that has various uses. PGA polymer is often used as a surgical suture material due to its ability to safely degrade within the body without causing complications.

Additionally, PGA polymer is used in tissue engineering and drug delivery systems. Its versatility and biocompatibility make it a preferred choice in the medical field.

Polyglycolide or poly(glycolic acid) (PGA) is a biodegradable, thermoplastic polymer and the simplest linear, aliphatic polyester. It can be prepared starting from glycolic acid by means of polycondensation or ring-opening polymerization. 

PGA has been known since 1954 as a tough fiber-forming polymer. Owing to its hydrolytic instability, however, its use has initially been limited. Currently polyglycolide and its copolymers are widely used as a material for the synthesis of absorbable sutures and are being evaluated in the biomedical field.

Some disadvantages of PGA polymer include its high cost compared to other materials, its limited flexibility and elasticity, and its relatively fast biodegradation rate, which can limit its long-term applications.

Additionally, PGA polymer can be difficult to process and shape, requiring specialized manufacturing techniques.

The advantages of PGA polymer include its biodegradability, high strength and flexibility, and its compatibility with human tissue.

PGA polymer is able to break down naturally in the body, making it an ideal material for medical applications such as sutures and tissue engineering. It also has a high tensile strength and flexibility, allowing it to be used in various manufacturing processes.

 Additionally, PGA polymer is highly compatible with human tissue, reducing the risk of rejection or other adverse reactions when used in medical implants.

PGA degrades faster than PLA because it has a higher rate of hydrolysis due to its chemical structure, which makes it more susceptible to breaking down when exposed to moisture and heat. Additionally, PGA is more prone to enzymatic degradation, further contributing to its faster degradation compared to PLA.

No, PGA is not hydrophobic. PGA stands for polyglycolic acid, which is a synthetic polymer that is known for its hydrophilic properties. It readily absorbs water and is used in various applications such as biomedical devices, sutures, and drug delivery systems.

The temperature at which PGA degradation occurs can vary depending on various factors such as the specific composition of the PGA, the presence of any additives or catalysts, and the duration of exposure to heat. However, PGA typically starts to degrade at temperatures above 150°C (302°F), with more significant degradation occurring at higher temperatures.

Polyglycolide can be obtained through several different processes starting with different materials: polycondensation of glycolic acid; ring-opening polymerization of glycolide; solid-state polycondensation of halogenoacetates; acid catalyzed reaction of carbon monoxide and formaldehyde.

Polycondensation of glycolic acid is the simplest process available to prepare PGA, but it is not the most efficient because it yields a low molecular weight product. Briefly, the procedure is as follows: glycolic acid is heated at atmospheric pressure and a temperature of about 175 to 185 °C is maintained until water ceases to distill. Subsequently, pressure is reduced to 150 mm Hg, still keeping the temperature unaltered for about two hours and the low MW polyglycolide is obtained.

Yes, we also provide industrial grade Polyglycolide material for our customer, there has two types: molding grade and film grade. You can directly contact us for more information.

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