Synonyms: Polyglycolide, PGA

CAS No: 26124-68-5

Appearance: yellow particle

Minimal order quantity: 30 gram

Polyglycolic acid, also known as polyglycolic acid, is derived from α-hydroxy acid. Polyglycolic acid has a simple and regular linear molecular structure. It is a simple linear aliphatic polyester with high crystallinity and forms crystalline polymers. Crystallinity is generally 40% ~ 80%, melting point is around 225 C, insoluble in commonly used organic solvents.

Polyglycolic acid is a synthetic polymer material with good biodegradability and biocompatibility. Unlike traditional polymer materials, such as plastics and rubber, polyglycolide will gradually degrade and eventually become water and carbon dioxide that are harmless to environment. The application of polyglycolic acid is mainly manifested in two aspects of biomedicine and ecology.

The biomedical applications are mainly manifested in medical sutures, drug controlled release carriers, fracture fixation materials, tissue engineering scaffolds, and suture reinforcement materials.

The application in ecology is to replace the traditional plastic widely used in the plastics industry as a completely biodegradable plastic. Polyglycolide is mainly used as a slow-release system to control the rate of herbicide release.


PGA polymer, or polyglycolic acid polymer, is commonly used in biomedical applications. It is a biodegradable and biocompatible material that has various uses. PGA polymer is often used as a surgical suture material due to its ability to safely degrade within the body without causing complications.

Additionally, PGA polymer is used in tissue engineering and drug delivery systems. Its versatility and biocompatibility make it a preferred choice in the medical field.

The main difference between PLA (Polylactic Acid) and PGA (Polyglycolic Acid) is their composition and properties.

PLA is a biodegradable and bioactive thermoplastic polyester derived from renewable resources such as corn or sugarcane. It is known for its versatile applications in various industries, including packaging, medical devices, and 3D printing. 

On the other hand, PGA is also a biodegradable polymer but is not bioactive. It is primarily used in the medical field for absorbable sutures due to its high tensile strength and quick absorption rate in the body. 

While both PLA and PGA share the characteristic of biodegradability, PLA has a wider range of applications and is more commonly used in everyday products compared to PGA, which is more specialized in medical settings.

No, the PGA (polyglycolic acid) used in various industries, including medical and textile, is not biodegradable. It is a synthetic polymer that takes a very long time to break down naturally.

Some disadvantages of PGA polymer include its high cost compared to other materials, its limited flexibility and elasticity, and its relatively fast biodegradation rate, which can limit its long-term applications.

Additionally, PGA polymer can be difficult to process and shape, requiring specialized manufacturing techniques.

The advantages of PGA polymer include its biodegradability, high strength and flexibility, and its compatibility with human tissue.

PGA polymer is able to break down naturally in the body, making it an ideal material for medical applications such as sutures and tissue engineering. It also has a high tensile strength and flexibility, allowing it to be used in various manufacturing processes.

 Additionally, PGA polymer is highly compatible with human tissue, reducing the risk of rejection or other adverse reactions when used in medical implants.

PGA degrades faster than PLA because it has a higher rate of hydrolysis due to its chemical structure, which makes it more susceptible to breaking down when exposed to moisture and heat. Additionally, PGA is more prone to enzymatic degradation, further contributing to its faster degradation compared to PLA.

No, PGA is not hydrophobic. PGA stands for polyglycolic acid, which is a synthetic polymer that is known for its hydrophilic properties. It readily absorbs water and is used in various applications such as biomedical devices, sutures, and drug delivery systems.

The density of PGA (Polyglycolic Acid) polymer is typically around 1.44 grams per cubic centimeter. However, it is important to note that the density can vary depending on factors such as the specific formulation, molecular weight, and processing conditions.

The temperature at which PGA degradation occurs can vary depending on various factors such as the specific composition of the PGA, the presence of any additives or catalysts, and the duration of exposure to heat. However, PGA typically starts to degrade at temperatures above 150°C (302°F), with more significant degradation occurring at higher temperatures.

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