Poly-L-lysine Hydrochloride
Structure: L-Lys-(L-Lys)n-L-Lys.xHCI
CAS No: 26124-78-7
Molecular weight: 5-300K Da
Purity: 99.9%
Appearance: white solid
Minimal order quantity: 10 gram
Poly-L-lysine hydrochloride is a highly soluble derivative of Poly-L-lysine, widely used in cell culture, drug delivery, and biomedical applications. This product, available in its hydrochloride salt form, offers excellent solubility, making it a preferred choice for researchers and industries requiring reliable performance in aqueous environments.
In cell culture, Poly-L-lysine hydrochloride enhances cell adhesion and growth by providing an optimal surface coating for cells. Its high solubility ensures uniform application, promoting stronger attachment and growth, particularly for primary cells, stem cells, and cancer cell cultures.
As a drug delivery carrier, Poly-L-lysine hydrochloride improves the bioavailability and solubility of hydrophobic drugs, facilitating their efficient delivery to target sites in the body. It plays a crucial role in controlled release formulations, ensuring drugs are delivered steadily over time.
Poly-L-lysine hydrochloride also exhibits antibacterial properties, making it useful in medical coatings, food preservation, and cosmetics, where it helps prevent microbial growth and enhances product safety and shelf life.
| Parameter | Specifications |
|---|---|
| CAS number | 26124-78-7 |
| Molecular weight range | 5,000–300,000 Da |
| Purity | >99.5% |
| Appearance | White Solid |
| Solubility | High solubility, readily soluble in water |
| pH (1% solution) | 5.5 – 6.5 |
| Boiling Point | > 200°C |
| Melting Point | Decomposes above 230°C |
| Packaging specifications | Available in 1g, 5g, 10g, or customized packaging |
| Stability | Store in a cool, dry place, away from direct sunlight |
| Application | Cell culture, drug delivery, antibacterial coatings, food preservation, and cosmetics |
FAQ
Most frequent questions and answers
Poly-L-lysine Hydrochloride enhances cell adhesion and growth by providing a uniform coating on culture surfaces. This improves the attachment and proliferation of primary cells, stem cells, and tumor cells, leading to more consistent and reliable results in cell-based experiments.
Yes, Poly-L-lysine Hydrochloride is an effective carrier for hydrophobic drugs. It improves their solubility and bioavailability, enabling better drug delivery and controlled release. This is especially valuable in pharmaceutical formulations that require sustained or targeted drug release.
Yes, Poly-L-lysine Hydrochloride is biocompatible and non-toxic, making it safe for use in cell culture and other biological applications. It has been tested extensively for safety and is widely used in scientific research without significant adverse effects.
Yes, Poly-L-lysine Hydrochloride has natural antimicrobial properties that help inhibit microbial growth. This makes it suitable for use in antibacterial coatings, food preservation, and cosmetic formulations, improving the safety and shelf life of various products.
Poly-L-lysine Hydrochloride should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept in an airtight container to prevent any contamination and maintain its stability for long-term use.
The typical concentration for cell culture applications is 0.01% to 0.1% depending on the type of cells being cultured and the specific experimental requirements. It’s important to optimize the concentration based on your needs to achieve the best results.
Yes, Poly-L-lysine Hydrochloride can be used in cosmetic formulations due to its antibacterial and moisture-retaining properties. It helps improve the stability and shelf life of products like creams, lotions, and other skin care items.
When stored under the recommended conditions, Poly-L-lysine Hydrochloride has a long shelf life. It remains stable as long as it is kept in a cool, dry place, away from moisture and heat.